Amphetamine Toxicity StatPearls NCBI Bookshelf

The goal is to help you understand your behaviors and why you use amphetamines. Involving family and friends during counseling can help support you and keep you from going back to using (relapsing). You may be unsuccessful at cutting down or stopping your use https://ecosoberhouse.com/ of amphetamines. You may continue to crave the stimulant even though you know they’re causing persistent or recurrent physical or psychological problems. If you notice you are taking more amphetamines than your recommended daily dose, talk with your provider.

  • For example, no study we reviewed here assessed specific populations such as indigenous peoples.
  • Additionally, levels of temptation and depression, but not anxiety, withdrawal severity, or treatment effectiveness, improved favouring treatment.
  • Generally, patient demonstrating only mild symptoms will not require extensive lab work or imaging and often respond to sedation and improve promptly under close observation.

Methylphenidate is less likely to cause addiction than other amphetamines. Amphetamine is contraindicated in patients with hypersensitivity to any component of the drug formulation. Other common side effects of amphetamine include insomnia, headache, dry mouth, tachycardia, increase in systolic blood pressure, restlessness, and irritability. Amphetamine is a medication used in the management and treatment of ADHD and narcolepsy. This activity reviews the indications, action, and contraindications for amphetamine as an agent in treating ADHD and narcolepsy.

Amphetamine-Based Products

They have a high potential for abuse and addiction but also have medical uses. Amphetamines are a class of stimulant drugs famous for their high potential for misuse and abuse. These stimulants have become increasingly popular over the past several decades, often as performance-enhancing or recreational drugs. By working with a reputable, research-based treatment program, individuals who have struggled with amphetamine abuse or addiction have a greater chance of moving forward in recovery and starting a future free from amphetamine abuse.

When amphetamines are used at higher doses and through routes that are not prescribed by a doctor, they can have severe adverse effects. There is evidence that amphetamine Amphetamine Addiction use to treat ADHD could slow growth in children. Minor effects on the cardiovascular system, including a rise in heart rate and blood pressure, may have long-term effects.

Adderall Addiction: Signs, Effects, and Treatment

The intoxicating effects of methamphetamine can also alter judgment and inhibition, which may lead people to engage in unsafe behaviors. Methamphetamine abuse may also worsen the progression of HIV and its consequences. In animal studies, methamphetamine increased viral replication; in human methamphetamine abusers, HIV caused greater neuronal injury and cognitive impairment compared with non-drug abusers. The reasons for lack of efficacy of clinically tested medications include heterogeneity of METH-abusing population and comorbidity between METH and other psychiatric disorders [19]. Furthermore, more clinical research is needed on the co-use of METH and opioids as well as how their combination affects overdose risk. Moreover, to increase the efficacy of pharmaceuticals, particularly dopaminergic, future studies should develop a way to increase the levels of dopamine D2 receptor, which are decreased in individuals chronically abusing METH [69-73].

  • In men who have sex with men, the antidepressant mirtazapine reduced MA use and high-risk sexual behaviours, despite low medication adherence rates [30].
  • You live at home with a strong support system and commute to a treatment facility multiple days a week for counseling and other forms of therapy.
  • Table 3 lists the pharmacotherapies reviewed, and the proposed mechanisms of action related to their use in studies of MA/AMPH dependence.
  • However, there were positive signals from several agents that warrant further investigation in larger scale studies; agonist therapies show promise.
  • MUD immunotherapies would have fewer off-target effects that are prevalent in pharmacotherapies because the blood-brain barrier is not permeable to immunoglobulins.
  • Treatment aims to help a person stop misusing drugs and improve their relationships with family, work, and society.
  • They receive advice from a trained therapist on how to avoid relapse and how to socialize in a drug-free environment.

Today, only dextroamphetamine, lisdexamfetamine, methylphenidate and mixed salts amphetamine are made for medical use. These drugs are used to treat attention-deficit/hyperactivity disorder (ADHD) in children and adults. Amphetamines were first introduced in the 1930s as a remedy for nasal congestion, and marketed over-the-counter as an inhaler named Benzedrine.

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